How good is the efficacy for in-the-wild malware?

Currently, our in-the-wild efficacy for malicious office files ("maldocs") is 90%+ (and growing). This means, our sandbox engines achieve the same result as a full-blown virtualization based sandbox (including bypasses for anti-analysis, sleep tricks, environment checks) in a fraction of time. Besides emulators for VBA macros, we offer emulation of javascript, vbscript, powershell and more.

For PE support, OPSWAT Filescan implements generic unpackers and full binary analysis with automated code extraction & analysis using diassemblers and symbol annotation.